advertisement

  1. This site uses cookies. By continuing to use this site, you are agreeing to our use of cookies. Learn More.

yet another failed try at mixing Lantus and Novolog

Discussion in 'Parents of Children with Type 1' started by wilf, Mar 4, 2009.

  1. wilf

    wilf Approved members

    Joined:
    Aug 27, 2007
    Messages:
    9,647
    I keep reading that a variety of medical professionals are suggesting that you can mix Lantus and Novolog or Humalog in the same syringe.

    At DD's request (we're always looking for ways to keep the number of injections down), I tried again tonight - gave a 2.5 unit Novolog bolus together with 8 units of Lantus. As has happened other times, the Novolog bolus seems badly delayed and DD shot up to 270 (now slowly coming down at 230)..

    Is anyone out there mixing these insulins successfully, and if so how are you doing it?
     
  2. mikesmom58

    mikesmom58 Approved members

    Joined:
    Feb 19, 2008
    Messages:
    272
    I've always been under the impression that Lantus should never be mixed with anything else. Everytime I any read info on Lantus it says that.
     
  3. etringali

    etringali Approved members

    Joined:
    Mar 27, 2008
    Messages:
    1,678
    Same here. We were told to not mix in the same syringe, and to give lantus in separate area from the novolog as it can affect how the N would work.
     
  4. Skyefire

    Skyefire Approved members

    Joined:
    Mar 1, 2008
    Messages:
    1,083
    There has been studies showing that it is ok, we were told by our endo that we could try it, but then we switched to Diluted Humalog, which could not be mixed.

    I can see how you would get your result Wilf, as Lantus crystallizes under the skin, for the long release...It makes since that other insulin's would get caught in the process. My worry would be, would it not only effect the Novolog but the lantus as well. I am all for less shots but if you are having this issue I would stop. I am sure it is one of those YDMV things :)
     
  5. hawkeyegirl

    hawkeyegirl Approved members

    Joined:
    Nov 15, 2007
    Messages:
    13,151
    I suspect that the people who do it successfully don't know that it makes a difference. That is to say, I suspect that they do it from the beginning and just adjust the ratios and Lantus so that it "works" for them, not knowing that the Humalog and Lantus would work a lot differently if they were not mixed.

    Jack HATED shots, but I could never bring myself to mix them.
     
  6. danismom79

    danismom79 Approved members

    Joined:
    Apr 21, 2008
    Messages:
    5,300
    I was thinking along the same lines.

    It's the same with Levemir. I mixed it once and it seemed to work, although it might have been a fluke. It never worked again. And I think I only noticed the difference because I didn't start off mixing them.
     
  7. Adinsmom

    Adinsmom Approved members

    Joined:
    Sep 12, 2006
    Messages:
    2,995
    Our Endo told us to try griving Novolog and Lantus in the same syringe to cut down on shots. It didn't work for us. The Lantus wasn't as effective and the Novolog lasted even longer then his usual 5 hr dia.
     
  8. Jordansmom

    Jordansmom Approved members

    Joined:
    Aug 23, 2008
    Messages:
    2,172
    I know someone who mixes them everyday, but I'm doubtful they'd be aware if it was working correcly or not. They aren't that conscientious.:(
     
  9. samheis

    samheis Approved members

    Joined:
    May 20, 2008
    Messages:
    517
    I don't know how it works, but that's the method we've been using since dx. He gets 2 mixed shots per day, at breakfast and dinner. I wish I could help you, but really this is the only way we know, so I wasn't even aware that it didn't work for some people!
     
  10. iluvmhp

    iluvmhp Approved members

    Joined:
    Mar 10, 2008
    Messages:
    1,582
    Our endo said it was ok. We never tried it, because she used two pens. Hope you can get some solid answers.
     
  11. AlisonKS

    AlisonKS Approved members

    Joined:
    May 16, 2007
    Messages:
    2,391
    we've mixed since diagnosis, TX childrens and OHSU have told us to do so.
     
  12. candise

    candise Approved members

    Joined:
    Feb 11, 2009
    Messages:
    431
    We mix Humalog and Lantus in one syringe and have since diagnosis. We were given specific instructions to add air to Lantus then Humalog. Draw from Humalog first then Lantus. We pretty much always use the same site for injection (back love handle area). We have had good success but do not know any different.
     
  13. danismom79

    danismom79 Approved members

    Joined:
    Apr 21, 2008
    Messages:
    5,300
    For people who mix, do you notice how long the Novolog/Humalog stays active? What about postprandial spikes with mixing vs other times of the day with just Novolog/Humalog?
     
  14. candise

    candise Approved members

    Joined:
    Feb 11, 2009
    Messages:
    431
    We have seen no spikes but Heaven is still honeymooning. She is around 100 before dinner eats 45 gram carb and takes Lantus6.5/humalog(sliding scale 4 usually) We test before bed around 3 hours later and she is back at 90-100. She wakes up around 100 in the morning.
     
  15. candise

    candise Approved members

    Joined:
    Feb 11, 2009
    Messages:
    431
    Oops - forgot she eats a 15 carb snack after bedtime testing. We also mix NPH /Humalog in the am shot.
     
  16. AlisonKS

    AlisonKS Approved members

    Joined:
    May 16, 2007
    Messages:
    2,391
    he needs way more novolog for breakfast vs the rest of his meals, that's the only thing that's different.
     
  17. fossmommy

    fossmommy Approved members

    Joined:
    Oct 16, 2008
    Messages:
    139
    Well, we have been mixing since DX and don't know any different, but we have only found one time of the day where there seems to be a jump after a meal and that's breakfast. Otherwise it seems to work really well for us. I hope you can find something that works for you!
     
  18. Andrew's Mom

    Andrew's Mom Approved members

    Joined:
    Oct 4, 2008
    Messages:
    479
    we started mixing when we started using i-ports and its been fine, but i am only mixing 1.5 u lantus with 3 to 4 u of diluted humalog i don't know if the amount makes a difference.

    Cathy
     
  19. buggle

    buggle Approved members

    Joined:
    Mar 24, 2008
    Messages:
    4,267
    We've never mixed. I like having the lantus site different than novolog site. We give lantus in the bum because we were told that it releases more uniformly from it. We give rapid in the arms or legs. Brendan gets two lantus shots a day, so he does get a lot of shots. So far, he hasn't complained so we haven't really had a reason to try mixing.

    Wilf, have you worked out the chemistry of how the rapid would be affected by being mixed into the lantus matrix? I'd think that it would make rapid behave more like regular insulin by slowing down release. I really don't see a way to mix them and get the effect that you expect with rapid. You could play around with pre-bolusing to see if you can match the peak with food better. I can't really think of any other way of addressing it.
     
  20. czardoust

    czardoust Approved members

    Joined:
    Oct 16, 2007
    Messages:
    2,178
    not mixing here, wouldnt try it.
     

Share This Page

advertisement