Well yesterday was the first day of our symlin trial and it went great. Sam only needs it for breakfast and only if the breakfast is over 20 grams. He took a 1/4 unit of symlin (small, yes I know but he is only 6 and using symlin is almost unheard of in a young child) We changed his breakfast ratio from 1:12 to 1:25 and everything worked great. No 400 blood sugar spike and no hypoglycemia. He took the symlin before he ate and the bolus after he ate. At one hour he was the mid 200's, two hours, mid 100's and three hours he was at a nice 128 (i think, somewhere around there). This is just what we wanted to happen. I am comfortable right now with the 200 spike...at least it is not 400. He does not need it at any other time in the day. I am glad that we have an endo that thinks outside the box and is willing to try new treatments!