We will be switching to novolog from humalog when we finish up this vial. Dr said we may notice some minor differences. What are your experiences? Does it last longer or work faster to the point where I should switch on the weekend? He did do a cartridge of novolog this summer when we were at the inlaws and all they had was novalog. It was the unpredictable summer, so I don't remember much (like I remember much of anything---ever!!) Sam is still pretty sensitive to insulin, not sure if that matters.