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Session 1: MODY: clinical heterogenity explained by genetic heterogenity

Discussion in 'Parents of Children with Monogenic Diabetes' started by Ellen, Sep 5, 2011.

  1. Ellen

    Ellen Senior Member

    Oct 22, 2005
  2. ChristineJ

    ChristineJ Approved members

    Dec 25, 2010
    Thanks for sharing these, Ellen. I particularly appreciated the other presentations specific to GCK MODY. In those presentations they discuss how GCK MODY is not always the benign "mild" diabetes with "no complications" that it's painted to be in many online sources and even in the first video here. As they mention in the GCK-specific videos, there is not enough data yet. While the risk of microvascular complications is thought to be lower, the risk of cardiovascular complications may not be. Also, not everyone with GCK mutation fits the "only a mild fasting hyperglycemia" profile.


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