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Santamaria Nano-particles Vaccine

Discussion in 'Research' started by sparty87, May 21, 2011.

  1. sparty87

    sparty87 Approved members

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    In this weeks webcast of JDRF's Annual Conference: Transformative Research in Type 1 Diabetes, Julia Greenstein mentioned Pere Santamaria's nano-particles vaccine.

    http://www.jdrf.org/index.cfm?page_id=114471

    I found this article back in February

    http://www.scientificamerican.com/article.cfm?id=nanovaccine-for-autoimmune-disease

    Its has been a year since the publication of the original paper, anyone know if they are progressing towards human trial ? The only reference I could find from 2011 is the following

    http://www.jdrf.ca/files/Publications/The_Cure/2011/The_Cure_Newsletter__March_2011_.pdf

    Sounds like they are still doing mouse cures, anyone know of progress toward human trial ?
     
  2. Ellen

    Ellen Senior Member

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    Thanks for this link in particular. I didn't have a chance to hear this before. They referred to the session in the morning - is there a link to that too?
     
  3. sparty87

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    Sorry. If there is a link to the morning session, I've not found it.
     
  4. joshualevy

    joshualevy Approved members

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    I was at a conference early this year, and there was someone their from the company that was working on Santamaria's idea. Parvus, I think the name was. My memory is dim that long ago, but I definitely got the idea that they were still many months away from a clinical trial. I got the feeling that it would start in 2012 at the soonest, but I don't remember if they said that, or if I just got that feeling from what I heard. Sorry I'm so vague, but I just don't remember.

    Joshua Levy
     
  5. joshualevy

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  6. sparty87

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    Parvus Therapeutics, the startup working on the Santamaria nanoparticles vaccine, updated their website since I last looked :

    http://www.parvustherapeutics.com/index.html

    • Seems that the T1D version of the Vaccine (navacimTD) is in pre-IND phase. Not sure if this means Parvus is involved with the FDA's pre-IND consultation program.
    • A bit of trivia on how they accidentally discovered the principle behind the vaccine while working on a way to load iron into the Pancreas to help image islet inflammation.
    • They have two new publications in 2011. But since I don't have a springer link account, I don't know about their contents.
    • Parvus claims to be well funded. I hope so...
     
  7. sparty87

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    Pere Santamaria's talk at world vaccine congress 2011

    http://www.youtube.com/watch?v=2zva5pS518Q

    Without a background in immunology, it was a bit hard for me to follow all of what he is saying, but the clip is still interesting.
     
  8. sparty87

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