Scott, I didn't specifically ask about highs post-pod change and priming orientation. To be honest, I basically blew off what the guy was saying about priming. It was the first I had heard it. It was also brought up in that series of questions that just drive me crazy - "Did you fill the pod with insulin?", "Did you get two beeps?", "Did you get the priming message?", "Did it beep after priming?" Are you serious?!? And they asked me these questions 10 times - one for each failed pod. We also struggle with highs post-pod change and have done many of the tricks mentioned here - including priming while vertical. I didn't see a difference when we primed that way - my son was still high after. What seems to work best of us is to give a "bump" of .75 units after a change before a meal or big snack (not a little snack). I think I'll have to do the experiment mentioned in the thread about filling the cannula on the Omnipod ? maybe priming one horizontal and one vertical. That would be very interesting to see.