My daughter is 15, dx type 1 at age 3. My son, has been participating in trial net since age 5, when my daughter was diagnosed. He just turned 18 in December. He has been antibody negative until his last screening; had a false positive for one antibody; the retest was negative. We as parents participated the first time thru, and since we came up negative, we did not need to rescreen in subsequent years. As far as "living in fear" idk that participating or not participating in a study will eliminate or create the fear...the fear is there as one of our children has this disease. I have always explained it to my son as that we will hopefully be able to discover what causes type 1, and perhaps prevent it in his children or his sister's children or perhaps his grandchildren. As far as whether he will develop it, I figure if he does, we are being proactive as we can be in testing...his pediatrician runs an a1c each year at his physical too, and we watch. I am hopeful that they will find a cure for type one someday, however, I think it is more likely they will discover how to prevent new cases rather than cure those that have had it for years. We still participate in the "walk for the cure" each year. Just because YOU may not get an immediate benefit from a study does not eliminate its value overall. A few blood tests over the lifetime is not going to cause so much drama in one's life. If it helps one child be prevented from getting type one in the future, it was worth it. And if no one is prevented from getting it...it still gave the scientists something to study. If no one participates how will we learn??? I think participating in the trial net study has value. If you choose not to participate, that is your option.