I know that NPH is not the common choice, but we did have our reasons for choosing it over Lantus. A couple of things about NPH that appealed to us was: Fewer shots More scheduled My daughter goes to a private school that has no nurse. I wanted to be able to send her snacks and lunch with her, but otherwise, make the presence of her diabetes as unobtrusive into her life as possible. I didn't want her to have to get shots at every meal. I thought that less testing would help with that. I felt that the scheduled nature of her school would lend itself well to NPH. Once summer came, we rationalized, we would change over to Lantus. The reality of the situation has been that it has been an absolute roller coaster nightmare. I had to quit my part-time job so that I could be available to run over and give her adjustments. She has had many, many frequent lows and highs. She has to be tested at lunch and snack time ANYWAY. The concept was great, but the reality of it has been absolutely nothing like what it seemed would be the case. They mentioned, though only briefly, the unpredictability of NPH's curve. I was just too tired (or stubborn, or stupid, or something) to hear it clearly and really internalize it. It has been an absolute nightmare. I don't have anything to compare it to, but now that it's been a few months, I often end up giving Kira extra shots, anyway. Corrections for high blood sugar... a shot when she wants to add some more food (and then it's math, math, math... and often calling in to make sure I did that right, even). The scheduling of it does not translate well to real life. It looks pretty on a graph, and it makes a nice promise... but it cannot deliver on any of the good sides of a rigid schedule. It can only deliver on the "locked into it every day" side. Yes, she has to be on a schedule, but the only one in this deranged relationship that has any leeway is the NPH. I think that it worked out well for her for the first few weeks when needle jabs were knock-down, drag-out fights. But now that she's wheedling, "I'll have an extra shot for it!" when she wants ice cream, it's almost torturous. So yeah. I just thought I'd share our experience with NPH, and how it held up none of its "promises" and has made everything far too hard. I know that most people will say, "I can't imagine why anyone would choose NPH," but we had what we thought at the time were good reasons. We wanted her day at school to be predictable and her not to have to test at every. single. bite. of. food. But that held to be not true and she still has to test every time we so much as look at her. And she has to eat exactly the right number of carbs--and you never know if she's on time with it or not (because NPH doesn't play fair). If you've considered NPH for the same reasons we chose it, please know now that in the end, it's just not worth it. It does not deliver!