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New numbers on the epidemic

Discussion in 'Parents of Children with Type 1' started by Snowflake, Dec 18, 2015.

  1. Snowflake

    Snowflake Approved members

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  2. rgcainmd

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    While I hate to see that the worldwide prevalence of T1D is increasing, I'm hoping that the growing number of people being diagnosed with Type 1 has a positive impact on the development of more advanced treatment technology and more research into finding a cure.
     
    Last edited: Dec 19, 2015
  3. Lakeman

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    The researchers are looking into a lack of gut diversity in the microbiome as a possible factor. Things that could lead to a lack of diversity are listed as processed foods, antibiotic use, and even c-sections. They are also looking to see if certain viral infections could be involved.

    It is certainly no simple cause that we can tease out easily and probably not the result of just one thing.

    Let's talk about the gut microbiome for a minute: Initially the gut bacteria are established when the infant is exposed to bacteria while traveling through the birth canal and then through the bacteria naturally present in breast milk. But we should add that when babies are young their gut is immature and allows particles to pass through it directly into the bloodstream. This is not a problem as long as the infant is only drinking breast milk AND the mother is not consuming things that are both harmful and passed on through the breast milk.

    As soon as strange food items are consumed by the breastfeeding mother or when foods are added into the babies diet too soon then the infant's immune system must handle the odd stuff in the bloodstream. But it does not end there. The permeability of the gut lining can also be effected by the things children eat later such as wheat or milk proteins (proteins with a morphine like effect) and these might even be the same proteins that are causing damage after they pass through the membrane. Add to that the general lack of traditional fermented foods (foods high in the good bacteria) that we used to eat lots of and now eat little of and one has a lot to think about. A couple of lacto-fermented foods are raw or cultured milk products, saurkraut and other naturally pickled foods.

    A possible scenario might be this: a child is born through c-section, raised on formula, introduced to various grains too early in life, fed an unbalanced diet in which grains make up almost half of all calories consumed, then fed foods which were not eaten by the human race until the last hundred years or so. This child is also exposed to a large variety of germs via vaccinations. The child is exposed to more germs than she ever would have had contact with naturally and the immune system does not react to the germs the same way it would if the germs were not in vaccinations. The result is that the TH1/TH2 balance of the immune system is out of balance so that the immune system does not react to future germs the child is exposed to in the environment the same way it otherwise would. When the child does get sick she is given antibiotics which kill both the bad germs and the good ones too. Much of our food is sprayed with roundup which does not kill human cells - it does kill gut bacteria. BT bacteria (found in BT-corn) also does not kill human cells but it does destroy the gut of insects and just might kill gut bacteria or even colonize it.

    There is a lot going on there and several factors might be needed before an autoimmune disorder might develop. If the cause is indeed mult-factorial then studies looking for any one cause could miss the connection. I don't know which things are the real causes and no one else really does either. At some point just about everything on that list was said NOT to be the cause - but something has to be the cause. Let's hope we figure it out.
     

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