Ok, so this is all second hand information,and filtered through a teen in college so I'm dealing with sketchy details indeed. My son saw a new endo at college today (last one was HORRIBLE, he's going to be traveling to see this one and...LOVE THIS...Skyping ). Both the endo and his wife/nurse are Type 1 so I feel a lot of confidence he's in good hands (vs the cattle call style treatment he had before at a major medical center near his campus). Phone conversation with the teen to find out how he liked the new office and he said she brought up using a drug to increase insulin sensitivity, Met..something. I'll assume metformin but if there are others please inform me. Like I said, details were sketchy at best! You guys just WAIT until you are sending your teens to MDs alone, it's maddening to those of us who like to be informed! He said she said something about injected insulin in high amounts leading to heart issues later and this drug helped the liver stop dumping so much sugar and therefore lowered insulin needs. This is news to me, I thought metformin increased sensitivity. What are the indications for metformin in Type 1 and would you consider it, in a well controlled teen with high TDD. Basal alone is close to 40, he's not eating a ton so TDD is probably 70-100, not horrible but no slacker either. They do a blood draw A1C so I don't have that, but his last one was 6.6, so he's doing amazing for a kid out on his own for the first time. To his credit he told her he didn't want to change anything until he saw his A1C and asked me to research it. So if there is recent research regarding metformin, injected insulin and later heart issues, etc, can you point me in that direction. Thanks.