DD has had D for over 2 years now and will be 10 years old tomorrow. We have sure noticed an increase in her insulin needs since day 1. Eg: started with TDD of 4 or so and now about 20-24 units TDD. The other day we realized her ISF should probably be changed due to the increased TDD. I changed it from an ISF of 10 to 6 (big jump in my opinion). Had to do a correction this a.m. and am nervous because it sure seems like a lot of insulin now. We used the 1800/1500 rule from Think like a pancreas. Where you take your TDD and divide into 100 (or something like that) to come up with an ISF of 6. Anyway, my question is: For a 10 year old does an ISF of 6 sound appropriate age-wise? She's 66 pounds. If you can chime in and tell me what your child's ISF is and TDD hopefully it will make me feel better and less apprehensive. I know YDMV but hearing other's TDD and ISF is reassuring. Also, can anyone chime in as to when the "Crazy Puberty" insulin rollercoaster starts? Is 10 years old too early for the start of crazy insulin needs?