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Iga deficiency ??

Discussion in 'Parents of Children with Type 1' started by irishmom, Dec 1, 2010.

  1. irishmom

    irishmom Approved members

    Sep 18, 2010
    Patrick was diagnosed in July .....we have been doing ok...met new end team and love them.....changed his whole regimen and were doing better...A1c was 5.3:). Now he is sick again( had strep a month ago and then influenza A). Ped endo called me at work on tues ironically I had just left a message five minutes before in regards to ketones....and she stated they had tested pat for celiacs disease....which I understand..my daughter was also tested a few years back...but stated they couldn't determine if he had it or not..because he is IGA deficient .....so brought him to LEDs and let her know and said this prob explains why he keeps getting sick:(. So just curious if anyone has had this problem...his numbers are a mess. Which I understand is due to being sick and we are testing blood and urine very couple hours...so just thought I would toss this out and see if anyone heard or knows something about it......his total IGA was 10

  2. mmgirls

    mmgirls Approved members

    Nov 28, 2008
    WELL, i have no personal insight, but it has to do with the immune system and it would seem as though he is immuno-compromised.

    That said, I beleive that Iga has allot to do with the intstinal tract and if celiac is a possibility, well them I would be heading for a biopsy to confirm and if so start on a gluten free diet.

    After awile of gluten free then the intestinal tract should repaire itself and the Iga may increase to normal levels and be no longer immuno-compromised.

    Hope you can figure this out quickly and get him well again soon.

    Good luck.
  3. deafmack

    deafmack Approved members

    Sep 22, 2006
    Hi, I know there is a woman on the Type 1 Boards on the ADA website that has IGA Nephropathy. Evidently she was born with it. Her username is TrishaO1. She is a really cool person and also has type 1 diabetes
  4. hdm42

    hdm42 Approved members

    May 1, 2008
    I wouldn't use the term "immuno-compromised", but rather he may have an immune deficiency. There is a difference.
    DS was dx'd with hypogammaglobulanemia before his D dx, and that has been stepped up to CVID (Common Variable Immune Deficiency) since then. He is very prone to sinus infections, which is how we discovered the issue. He sees an immunologist, and they have had him on prophylactic antibiotics to help lessen the number of infections. At the moment, he's off the meds (for a number of reasons). Yes, he tends to catch everything and we have to be vigilent, but it's manageable.

    I hope it's something simple that will be easily resolved for you. Feel free to pm me if you want more info.
    Last edited: Dec 2, 2010
  5. Colleen

    Colleen Approved members

    Apr 18, 2008
    I have CVID and my youngest son has IgA and IgM deficiency. PM me if you want to talk.
  6. Kaylas mom

    Kaylas mom Approved members

    Apr 14, 2010
    My son also has CVID and the other kids in the family and myself (including my d child) are IgA def.
  7. sheila

    sheila Approved members

    Jul 27, 2006
    My dd IgA is low as well. Last lab work it was 6. They sent us to another specialist who did more lab work......they are just keeping an eye on it for now. They did tell us that if she ever needed a blood transfusion to tell them because the blood would have to be filtered or her body would reject it.
  8. twolittleladybugs

    twolittleladybugs Approved members

    Apr 26, 2008
    I don't have much to add to what everyone else said. I agree about pushing for a biopsy if you suspect celiac. The tests they use for celiac diagnosis are IgA based, so you can get a false negative if you're IgA deficient. There's also a higher percent of people with celiac who are IgA deficient (or vice-versa). Also, when I was reading about it (we thought Emily might be IgA deficient at one point), I think I read there can be an issue with certain immunizations "sticking." I'm sure some of the people living with it will have tons more info than I do.

    Good luck,

    Emily 8--dx @ 2 1/2, multiple food allergies
    Kaitlyn 4
  9. kiwiliz

    kiwiliz Approved members

    Sep 25, 2008
    I thought Influenza A - specifically swine flu - caused a low Iga - perhaps it is a result of rather than a cause of.?
  10. mmc51264

    mmc51264 Approved members

    May 2, 2006
    My non-D child is Iga low and was tested (neg) for celiac and many other things. He has absorbtion issues and a very picky eater, but otherwise normal. He is taking enzymes to help him digest and absorb foods (pancrease/pancrealipase; sometimes called Creon). That has helped some.
    As far as immunocompromised, he has had 2 colds in 4 years and has not been on any antibiotics since he was 3 (I think) LOL healthiest one in the family.

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