Brenda, thanks for posting the links above. Dd goes to Barbara Davis (which is part of UC Denver), and Dr. Chase (the author) still sees patients - though mostly research study participants. Anyway, after posting I was thinking about how the instructions we're given at endo appointments differs from the medication insert. That, like many of the respondents to this thread, says to give the full dose (1mg) for over 55 lbs. This is what the chapter Brenda linked to says, and what the clinic tells patients and families for glucagon dosing to treat a severe low: < 6 years old = 0.3cc or 30 units (0.3mg) 6 - 18 years = 0.5cc or 50 units (0.5mg) > 18 years = 1.0 cc or 100 units (1mg) We just had an endo visit two days ago, and both the CDE and PA assured us that giving dd the full syringe would make her far more miserable than need be, but there isn't a risk of overdose. I do wish they'd print the weight guidelines they use, but it isn't the 20kg / 55lb guideline listed in the med insert.