Hi everyone! I need some help troubleshooting what's going on with my daughter the past 2 nights. She has been going super high (300s), starting somewhere between 8pm (her bedtime) and when I check her at 10. Two nights ago, none of the corrections or increased temp basals I set did anything at all, I did a few throughout the course of the night. I figured the site was going bad as we were due to change anyway, so I changed out everything, insulin, tubing, and site yesterday morning. she was in range most of the day, except a 230 after school, which she later informed me was because she ate some of her friends grapes at afternoon snack, oy. But the rest of the evening all was fine, she didn't eat anything unusual and everything was bolused for. Bedtime was 140. Then she was 280 at 10pm, which I corrected for. At 3am she was 356!! I did a correction and then decided to check her pump and i thought I saw some air bubbles, so I re primed the tubing and then set a +30% temp basal. She was 167 at 6:30am. Any insight from the experts?? Are her basal needs increasing? Or do numbers that high indicate problems with the delivery (ie air bubbles)? Also, I'm wondering if the ISF is not right. When we were on MDI, it was 1unit:100pts. This is what we have the pump set at during the day, but the endo's office had us set it for 1unit:200pts at night, i'm wondering if we should change it to 150 or 175. I'm dreading the same thing happening to her tonight.