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Glycomark test, how many use it?

Discussion in 'Parents of Children with Type 1' started by Toni, Feb 10, 2010.

  1. Toni

    Toni Banned

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    Joslin Study on Diabetes Test for Children

    FOR IMMEDIATE RELEASE

    MULTIPLE PROMINENT RESEARCHERS AT ADA FIND 1,5-AG DETECTS POTENTIALLY DANGEROUS GLUCOSE SPIKES IN ADULTS AND CHILDREN WITH DIABETES;

    Reinforces need for testing beyond A1C, provides short term tool for glucose control

    June 6, 2009, New Orleans, ADA?New research findings from two prominent research organizations today confirmed that 1,5-AG, the GlycoMark test, accurately identifies potentially dangerous blood sugar spikes in adults and children with Type 1 (insulin dependent) and Type 2 diabetes, while A1C results suggest they are in modest control.

    The findings were announced at the American Diabetes Association Scientific Sessions and come out of two independent studies from pediatric endocrinology researchers from the Joslin Diabetes Center who looked at Type I children and young adults, and a team of international researchers sponsored by three major international diabetes organizations who looked at adults with both forms of diabetes from 10 centers worldwide. Each study validates the use of 1,5-AG for identifying patients with glucose excursions in both clinical and research settings.

    Joslin?s results were presented at an ADA poster session and are included in the abstract (A-1802-P) entitled, ?Utility of 1,5-Anhydroglucitol (1,5-AG) in Assessing Glycemia among Youth and Young Adults with Type I Diabetes (T1D) .? The abstract is available online at http://ww2.aievolution.com/ada0901/index.fm?do+abs.viewAbs&abs=6200.

    According to lead author, Dr. Sanjeev Mehta, MD, MPH, researcher and pediatric endocrinologist from the Joslin Diabetes Center and Instructor at the Harvard School of Medicine, ?The 1,5-AG test informs families about glycemic performance in a shorter period of time than A1C and may help inform decisions about more aggressive measures, such as continuous glucose monitoring.? The test reflected significant hyperglycemic excursions at A1C<8 and indicate a need to learn more about glycemic variability.

    Lori Laffel, MD, MPH, Chief of Pediatric, Adolescent and Young Adult Diabetes and Endocrinology from the Joslin Diabetes Center and Associate Professor of Pediatrics at Harvard University School of Medicine said, ?1,5-AG gives another opportunity to understand the diabetic state in order to optimize control, assess therapies, and look at outcomes.?

    ?1,5AG is useful for patients with suboptimal glycemic control to assess short term therapeutic or behavioral interventions. For patients in moderate control, it also provides young patients and families with positive reinforcement that therapy is working.?

    Also announced today were new findings from international researchers that definitively established the Glycomark test (1,5 AG) as the only blood test to accurately measure dangerous glycemic fluctuations in patients with diabetes that are undetectable by A1C. In the abstract (A-882-P) entitled, ?1,5- AnhydroGlucitol (1,5- AG) Concentrations and measures of glucose control and variability in T1DM and T2DM patients,? researchers recommend using 1,5-AG as an adjunct to the hemoglobin A1C test for moderately controlled patients (A1C <8), which represents a change in paradigm for diabetes testing. The abstract can be found online in the ADA abstract compendium: http://ww2.aievolution.com/?do=abs.viewAbstabs=5737.

    Eric Button, President of GlycoMark said, ?Averages can be misleading, and A1C?s can look normal when GlycoMark (1,5-AG) reveals dangerous glucose swings that can go undetected.?In response to the Joslin study findings he said, ?There aren?t a lot of studies on children and youth with and without diabetes, and the Joslin study found significant benefit with using 1,5-AG for glucose management for children and young adults with diabetes, and confirms findings from our global study which looked at adults.?

    The international research was sponsored by the American Diabetes Association (ADA), International Diabetes Federation (IDF) and the European Association for the Study of Diabetes (EASD) and took place in 10 research centers worldwide.

    Both studies add to the evidence that testing beyond A1C is crucial, and 1,5-AG can be a beneficial adjunct to diabetes testing and suggest that a new paradigm for diabetes management is in order.

    Media Contact:
    Margie Ross Decter at ADA:
    cell- 617-501-5325
    email- mrossdecter@enzymeinc.com
     
  2. mmgirls

    mmgirls Approved members

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    do a search, i think Darrly's ped does this test.
     
  3. Darryl

    Darryl Approved members

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    We had it done last June, it was 10.4 (over 10 is "good control", 15 is non-diabetic).

    I don't think we'll do it again... it only shows the last 1 to 2 weeks of variability, and nothing we didn't already know from the CGM data. I suppose it could be useful for someone not using a CGM, but even then every week is different.
     
  4. Toni

    Toni Banned

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    Test must be done every two weeks, then? Hmmmm.... is it a blood test. Expensive? Our endo does not use it so far.
     
  5. Darryl

    Darryl Approved members

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    You would not do this test every two weeks, it is an intravenous blood draw. We did it as part of the annual IV blood tests. That's why I am not sure how useful it is, because you would only do it once in a while.
     

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