I wrote a few weeks ago about my friends dog and got some great advice. The dog has had d for about 3 months. He weighs 75lbs and is on 22novolinN in in the am and pm with specific food amounts given after. I go over every day to check the dog's bs because it is very difficult for my friend to get blood by herself. We usually check before the dinner shot. The lowest bs we ever got was 384. The numbers hover in the 400's. The vet is very hesitant to increase the insulin. He keeps telling her the high numbers could be rebounds. If it was my dog I would be increasing the insulin steadily over time but my friend is afraid. The dog is so sad and tired. Any suggestions would be appreciated.