My DS is turning 4 in a month, and was diagnosed with DMT1 in mid October. He wears a Medtronic Minimed pump and an Enlite sensor. His correction factor is (since October) 200 (one insulin unit brings BG down 200mg/dl). He takes Humalog (100 IU per ml). Last week I observed whether this correction factor was adequate for him. One time his BG was 180 three hours after eating, so I gave him 0.4IU (we correct to 100). After about one hour his BG was already coming down, and after two hours he was already close to 100. However I have observed several times in the past that when his BG is above 250 one correction alone doesn't seem to do anything. For instance, today his BG was almost 300 1.5 hours after eating (he usually doesn't go above 250 one hour after eating), so the pump calculated the bolus as 1IU minus 0.3 IOB, and pumped 0.7 IU. One hour 15 minutes later the sensor hadn't dropped at all and his BG was 270. I pumped again, this time the pump calculated 0.85 IU minus 0.4 IOB and pumped 0.45 IU. We keep having these situations over and over again, and in our experience if he hasn't come down from the first correction, the second rarely works, so I also put a temporary basal of 125% (increasing his basal from 0.1 IU/h to 0.125) for one hour. One and a half hours later his BG was 56. Do you find that when BG is so high, they need more insulin than what you'd put if it wasn't so high? Is this behaviour normal? How do you go around it? Do you have a lower correction factor for bringing down those high numbers? If so, how much higher? Is there some sort of insulin resistance that is somehow triggered by high BG? It would be nice to know what I can do in such a situation without having to wait for the BG to go down without knowing whether it will come down at all, or how long it will take! Thanks for any insights you might have.