https://www.nejm.org/doi/full/10.1056/NEJMc2022226 New England journal of medicine letter. Ifyou don't have access just go to sci-hub.se and copy the link. Interesting case where the boy was post honeymoon and recovered with Ruxolitinib 10mg 2x per day. Because he had multiple conditions the doctors did a whole genome sequencing. They run about 1000 dollars and I think it's rare to get insurance to cover it without a strong doctors order. Anyway they found he had a STAT1 gain-of-function, whatever that means, and prescribed Ruxolitinib. I don't think this will help the large majority of kids and adults with t1d. I just thought it would be interesting to share. I am also curious if anyone has experience ordering a whole genome sequencing. Seems like there are a lot of shady companies offering the service. Plus the data isn't much good anyway without a trained person to analyze it.