DS had a sedated MRI a few days ago and the sedation team used this awesome patch on him. It was like a giant bandaid with a numbing agent inside - a lidocaine/tetra-something blend. They put one on the inside of his elbow and one on the back of his hand. 15 minutes later, they peeled it off and put in his IV. He watched them do it and didn't feel a thing. It was amazing. Only thing he felt was heat - by the end of the 15 minutes it felt pretty warm - and it wasn't uncomfortable. I asked what it was and then talked to my endo's office about it today. DD has never used a numbing agent. I've used EMLA on a blood draw and thought it was worthless - skin was numb but everything underneath it wasn't. So...the endo agreed to write a script for the Synera and she did...but she also warned that it is a lot more expensive than EMLA and offered that as well. I left with a script for each and a plan to call insurance and see how they compare. Well, the Synera is $150 for 90 days. The EMLA is $10. Obviously, if the EMLA will work (as in, make the inset painless) then I'll fill that script. If not, I'll pay the extra and get the Synera. Based on seeing my son's reaction, I'm convinced the Synera will work. But...$10 is better than $150 If you've used both EMLA and Synera, how would you compare them? Wildly different or fairly similar? If the Synera is my best bet, I don't want to waste the time (3 weeks to get mail order on EMLA, then a few test days, then 3 weeks to get mail order on Synera.) Thanks for your help!