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Allergic to Insulin?????

Discussion in 'Parents of Children with Type 1' started by mom2cjh, Aug 11, 2008.

  1. mom2cjh

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    My 7 year old was diagnosed 8/23/07. Started with Lantus/Novolog and within weeks developed rash on legs where we were doing his Lantus shots. Spoke with doctor who said it would be rare but after seeing the rash switched him to Levemir/Novolog. By Dec. 2007 started getting rash from Levemir but we had then switched to Omnipod with Novolog...just in time we thought. Now in the last few months complaining of itching/hives under Omnipod. Was hoping it was due to adhesive...have tried skin and IV prep, tegaderm, benadryl spray (recommended through CWD site) and waiting for bard barrier wipes in the mail...but son still complains of itching around cannula and when pod comes off usually a welt in that area and after much itching a lot of irritation to the skin. At last endo appt. the doctor said we may have to try Humalog which he knows the pharmacist have a formula to "desensitive". Just wondering if anyone else has this problem. We have an appointment in a week for our 3 month.
     
  2. Mody_Jess_Pony

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    Maybe it's an allergie to whatever the syrnge or canula is made of?
    I know some people have an allergie to the teflon sites are made of that prehaps could be it. That and possibely the adhessives possibly as well.
     
  3. Seans Mom

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    I have read of an allergy to insulin, been so long I can't remember which site and which insulin it was. Novolog has been the one constant in all the rashes, I'd give Humalog a try. The allergy to the cannula is another I was thinking, but would try the Humalog first.
     
  4. s0ccerfreak

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    I know someone who is allergic to synthetic human insulin, but I can't remember what they have her taking now.
     
    Last edited: Aug 11, 2008
  5. mom2cjh

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    I thought of the cannula also but since he had an allergy to Lantus, and then Levimir, and then Novolog. I did forget to mention that we were now using Apidra and the same thing but a little less severe...although he has had great #'s. We get to about 2 days before any major complaints. Just wondering if there is any difference in using Humalog? Does it act as quickly as Novolog/Apidra? Since we had used almost all known skin barriers not sure if it is the adhesive...have even used tegaderm over entire site...so I think it is either the cannula or insulin. To bad we can't just stop them and see if it clears up:)
     
  6. Seans Mom

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    It's my understanding that Novolog and Humalog work the same, Apidra is supposed to work faster then the logs and have a shorter DIA time. Unfortunately with the omnipod you have no other set options. However, if the Humalog doesn't solve the problem you may want to see about doing a trial run w/ a traditional pump using the steel needle set to rule in/out the cannula allergy.
     
  7. StillMamamia

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    I would rule out an allergy to the needle also. I don't know if you can have different needles for the Omnipod though.
    Insulin allergy can occur, but I think it's rare. It's usually an allergy to the additives in the insulin to prevent it from deteriorating, I believe. Could it be the insulin is no longer good?
    Also ask the endo for IV prep and adhesive remover for sensitive skin.
     
  8. misscaitp

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    If it is not an allergy to the cannula or needle. Then I would think that it is a allergy to Synthetic Human Insulin. Which is what is used in both Eli Lilly insulin products and Novo Nordisk insulin products.
     
  9. mom2cjh

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    An allergy to synethic human insulin doesn't sound too good...but I suppose that is what the doctor was talking about 3 months ago when we tried the adhesive approach. Should be an interesting visit next Monday. I just feel bad for my son b/c sometimes it takes everything in his power not to rip his pod off and throw it. Changing it every 2 days does help somewhat. I just know that it is awful to need to itch something and you can't!!! Will probably try a "densensitived insulin" and see how that goes....if not we'll have to discuss pump options...he is pretty set (and us also) on staying with the Omnipod (thinks it is pretty cool he has the same as Nick Jonas!!!) We'll take it step by step. Thanks for the replies
     
  10. TheFormerLantusFiend

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    The person most of you are probably trying to think of is Molly. She writes this blog: http://damdiabetes.blogspot.com/, she uses a service dog, and she has steroids mixed with her insulin in the pump because she is allergic to insulin.
     
  11. mom2cjh

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    Thanks for the response...I emailed Molly from her blog to see what the symptoms were of the insulin allergy. Hopefully we can rule that out.
     
  12. tracy true

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    hi , jake has a local reaction to all his injections . He gets a little red lump about the size of a penny . Never had this in the beginning , spoke to his specialist he said we could inject him with anything and this would still happen . Just on of those thing were jake is concerned . They dont bother him , not icthy or anything like that and go within 24 hours .
     
  13. mom2cjh

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    Molly responsed to my email very quickly. She said her allergy started mild with rash and hives also...then later her lips. Currently she is using Humalog with steroid injection for allergy reaction. Time will tell if his reaction is going to get worse....if it is truly an allergy usually gets worse over time. Thanks for all of your help.
     
  14. ADHDiabetic Mom

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    My son is allergic to nickel -- even the trace amounts found in stainless steel. He can't wear jeans with snaps, a watch, any jewelry except for James Avery (they use copper instead of nickel as an alloy in their sterling silver), or any metal dental appliances.

    If he does not take benedryl every night and Claritin in the morning (or Zyrtec -- that works, too), he starts to have allergic reactions at his insulin injection sites from the nickel in the stainless steel needles.

    Could this be the problem?
     
  15. mom2cjh

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    I think I will give that a try and see if it helps. Was giving him allergy medicine nightly recently due to extremely itchy throat...didn't pay attention if he complained less about pod itchy. Have suggested benedryl...need to get the pills...because he doesn't like the flavor of the liquid...thankfully he has no problem now with small pills. I'll give it a shot!!
     
  16. Tweety8

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    Yes! Yes! This happened to my Dd too!


    mom2cjh,

    My daugther was put on Novolog and Lantus in February right at diagnosis. For two months, teh same exact thing you are describing happened to her. I was a wreck, really afraid she would be allergic to insulin. As soon as we switched to Humalog, nothing. not one reaction, not one rash, no bumps, no itching. It was instant with her. Thank goodness for Humalog. Anyway, I did some further research with my pediatrician... Lantus and Humalog do not have a certain ingredient called Disodium Phosphate Dihydrate. I think this is the name, but I don't have my notes with me, but if I recall, this is the ingredient in Novolog and NOT in the others. Anyway... please know you are not alone in this. I went through the same thing and it was totally an allergy to Novolog for us.

    I hope you guys will do just fine on the Humalog.

    Kristin
     
  17. Tweety8

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    Yes, that is what happened to my Frankie. She would get hives on her face, and legs. NOthing in the injection sites when we were doing MDI's. I swear, as soon as we switched to Humalog, she was fine - 100% no problems.
     
  18. Kent T

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    Hi,

    I have the same issues here. I have a bad insulin allergy problem (I had to switch from NPH/Humalog) to NovoLog/Levemir some years ago. I now pump with the Animas IR 1250. I had to switch from Comforts and Insets to Contact Detach sets (No cannula here, steel needles). Allergic to the cannulas. Partly related to my being latex allergic (I also have spina bifida). My wife (who also has spina bifida) has the same issues as I do. So far, our 2 adopted children (one 10 months old and one 4 years old and have spina bifida) don't have issues yet with cannula allergies. They are latex allergic.
     
  19. mom2cjh

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    Thanks for the replies...last night tried bard barrier wipes and we'll see what happens by tonight/tomorrow. It helps to know others have made it past these rashes. Will see if we can get Humalog as a trial on Monday...if not we'll have to see about the cannula.
    Thanks again for your responses.
     

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