Michele'sMom posted this video link in General Discussion. I think it is worth posting again. http://www.tudiabetes.org/video/tudiabetes-live-interview-with-author-gary-scheiner Gary insists 100-120 grams of carbs are needed everyday just to feed the brain and nerves plus more to fuel the muscles and activity. He says one has worse control with a low-carb diet as the conversion of protein to glucose is dependent on too many variables and too unpredictable. He thinks that less than 80 carbs a day is not even enough to just fuel the nervous system.....dietary protein is meant for other uses...muscles, bones, growth , enzymes, etc. not as an energy source. As for the effect of larger doses versus smaller doses of insulin...he says doses say, 10 times larger (20units vs 2 units) take longer to start, peak and finish, but that is the only difference. Definitely worth the hour you will spend listening to this.