I am not a scientist, but an analyst and this is how I see we got into this mess. JDRF informed us there ad is based on the findings of Dr. Cryer. Here is a little about him: "Biography A graduate of Northwestern University and its medical school with training in internal medicine at Barnes Hospital and in endocrinology and metabolism at Washington University, Dr. Cryer has been a member of the faculty since 1971. He served as program director of the General Clinical Research Center from 1978 to 2006 and as Director of the Division of Endocrinology, Diabetes and Metabolism from 1985 through 2002. He has been the Irene E. and Michael M. Karl Professor of Endocrinology and Metabolism in Medicine since 1995. A past president of the American Diabetes Association and a former editor of its leading journal, Diabetes, Dr. Cryer's research has been recognized by the Banting Medal for Scientific Achievement of the American Diabetes Association, the Claude Bernard Medal of the European Association for the Study of Diabetes, an honorary doctorate from the University of Copenhagen and a MERIT award from the National Institutes of Health. Research Interests The themes of Dr. Cryer's translational research are studies of the physiology of glucose counterregulation - the mechanisms that normally prevent or rapidly correct hypoglycemia - and of its pathophysiology in type 1 and type 2 diabetes, and the relationship of the latter to clinical hypoglycemia in diabetes." Since this started, I have been reading a ton of research reports and almost every one of them references Dr. Cryer's work. So, members of this forum think they know more than Dr. Cryer and just about every other researcher in this field???? The problem is that a percentage of Type 1's experience more severe lows than the general Type 1 population. The DCCT trial did not include PWD with a history of severe lows. The other problem is that until CGMS, it was hard to say what the blood sugar reading was at the time of death. Now they have proof that lows cause death, cause heart issues, etc. I am surprised there are not more deaths related to alcohol use and driving. My DD is getting inundated with those messages and not even doing either yet. In my little world, I have heard of several Type 1 deaths in the last 2 years. Usually, you hear "diabetic coma" as the cause of death. Does that mean a coma from a low or DKA? I worked for an insurance company for a short while and saw a death claim that stated diabetic coma as the cause of death and when I read the 42 year old man's medical reports he had an A1C of 6.5. There was a 16 year old die in her sleep and 2 other people I have talked to told me of parents who lost their child to it. My DD's coach lost his 50 year brother to DKA. He had a virus and his partner of 12 years who was a nurse thought it best to let him sleep it off, neither of them thinking of ketones. A college teacher I had also died of a diabetic coma (he may have been a drinker). I met a young woman last month who told me she has had 52 emergency visits/ambulance calls. She just got a pump and was hoping that would change. The Type 1's on the forum have bravely been telling you their stories about how they tank so fast, it was lucky someone was around to assist. The risk is real and the ad is not lying. Of course we would much rather have a cure than have our CWD hooked up to an AP, but we might have to hope for the AP in the meantime.