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What is causing the increase of type-1 diabetes? (part 1)

Discussion in 'Research' started by joshualevy, May 19, 2013.

  1. sgh

    sgh Approved members

    Joined:
    Apr 11, 2010
    Messages:
    77
    rubella/viruses

    Yes, Dr. Gale argues that congenital rubella can lead to diabetes in people (among other effects) but it's not necessarily autoimmune (type 1) diabetes. One problem in figuring this out is that back when pregnant women were getting rubella they weren't testing for antibodies in people with diabetes (they hadn't discovered autoimmunity yet). So although the kids did often get diabetes, we don't know what type it was for sure. And Dr. Gale tends towards the conservative side, that is, it takes a lot of evidence to convince him of anything. I'd be more inclined to argue that there's pretty strong evidence that viruses can trigger type 1 in people; he is more skeptical.

    Anyhow this is rather tangential. There hasn't been an increase in viruses that have been linked to type 1, more likely a decrease, so even if viruses can trigger type 1, which they probably can, it's hard to see how viruses alone could explain the increasing incidence. But they could be acting in combination with other factors, and I'm sure they play a role in some people.
     

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