From http://www.sciencedaily.com/releases/2014/09/140916182216.htm A study of more than 18,000 patients with type 1 diabetes has shown that use of insulin pumps to administer insulin rather than treatment with multiple daily insulin injections results in a 29% reduction in all-cause mortality and 43% reduction in the risk of fatal cardiovascular disease (CVD, i.e. coronary heart disease or stroke). The researchers found that patients with insulin pumps were 29% less likely to die from any cause than those with multiple daily insulin injections, and also 43% less likely to develop fatal CVD, with both results being statistically significant. Specifically looking at fatal or nonfatal coronary heart disease, pump use was associated with an 18% risk reduction (borderline statistical significance). Non-significant risk reductions with pump treatment were seen for fatal/nonfatal CVD combined and for non-CVD mortality. Further info from http://www.medscape.com/viewarticle/831836 However, she (Lead author of the study, Soffia Gudbjörnsdottir, MD, of the University of Gothenburg, Sweden) cautioned that the patients using pen injections were different from those using pumps: the former had a slightly lower educational level, were slightly older, had a longer duration of diabetes, higher blood pressure, and more previous cardiovascular disease, although the same HbA1c. Although they used propensity-scoring to balance the 2 groups and compare them fairly, they may not have eliminated all confounding, she noted. Asked if she thought the pump itself saves lives, she said: "I don't think it's the pump per se; it's everything that comes with the pump. In our country, pump users are invited to diabetic school when they start the pump, and it's easier to contact a doctor or nurse on weekends, so you have better care."