My 18 mo old is newly diagnosed. We have been doing ok, using carb to ration of 30 carbs to 1 unit of Humalog. Then the nurse told me that I had to change insulin once a month and mine was out for close to 2.5 mo. So I quickly switched and opened a new bottle that I kept in the refrigerator. Then strange things started happening... It seemed liked it was not working at all... It takes at least an hour to start lowering sugar, and I increased the ration to 15 carbs to 1 and he is still hyper most of the time... Could it be bad insulin??? That's the only thing that makes sense to me. I called the hospital and they say that he probably needs his dose adjusted... But it makes no sense!!!! For example had woke up with 230, I have him two units and 30 min later it was still 230! I was waiting for it to start going down before giving him breakfast.