I am perplexed probably more than I need be. We just got all our son's labs back and W has no autoantibodies except for slight showing of insulin autoantibody which I understand can be present in anyone on an insulin regime. A search here showed he isn't the only Type 1 without autoantibodies, but the more I read the more questions I have. Two endo's I've spoken to don't seem to have many answers either. Neither think a gene mutation could be the cause of his diabetes and neither can fully explain why some type 1 kids don't have autoantibodies. Doesn't it defy logic? Does anyone have any further insight?