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Islet Transplant without antio-rejection drugs- large primate results

Discussion in 'Research' started by fishface326, Aug 5, 2019.

  1. fishface326

    fishface326 Approved members

    Joined:
    Jun 5, 2018
    Messages:
    7
    Thought this sounded like good progress:

    https://medicalxpress.com/news/2019-08-anti-rejection-drugs-transplant-recipients.html

    In a study published in Nature Communications, researchers at the University of Minnesota Medical School's Department of Surgery and Schulze Diabetes Institute, collaborating with colleagues at Northwestern University, have maintained long-term survival and function of pancreatic islet transplants despite complete discontinuation of all anti-rejection drugs on day 21 after the transplant. This study was performed in a stringent preclinical transplant setting in nonhuman primates, one step away from humans.

    This new study capitalizes on the unique attributes of modified donor white blood cells, which were infused into transplant recipients one week before and one day after the transplant, thereby recapitulating nature's formula for maintaining the body's tolerance of its own tissues and organs. Without the need for long-term antirejection drugs, islet cell transplants could become the treatment option of choice, and possibly a cure, for many people burdened by type 1 diabetes.
     

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