Very encouraging article for those who maintain tight BG control published this week in the Archives of Internal Medicine. This is the abstract. The full text article is here: http://archinte.ama-assn.org/cgi/content/full/169/14/1307?home. I can't publish the document here as it is only available for purcase. It contains more graphs, discussion, and statistics but the conclusion is fairly clear. Modern-Day Clinical Course of Type 1 Diabetes Mellitus After 30 Years' Duration Arch Intern Med. 2009;169(14):1307-1316. Results After 30 years of diabetes, the cumulative incidences of proliferative retinopathy, nephropathy, and cardiovascular disease were 50%, 25%, and 14%, respectively, in the DCCT conventional treatment group, and 47%, 17%, and 14%, respectively, in the EDC cohort. The DCCT intensive therapy group had substantially lower cumulative incidences (21%, 9%, and 9%) and fewer than 1% became blind, required kidney replacement, or had an amputation because of diabetes during that time. Conclusion The frequencies of serious complications in patients with T1DM, especially when treated intensively, are lower than that reported historically.