DD4 was diagnosed 13-14 months ago at age 3y2m. Obviously it was miserable but we did reach a reasonable steady state with our roughest times mostly during any attempted vacation/travel. From a few weeks after diagnosis until a few months ago we had pretty stable dosing. We started at 1:60g for humalog for meals and 1 u lantus. Initially that usually meant a half a unit for most meals up to .75 unit and this was actually more of an overbolus and we had to give her a snack of 10-15 grams within 2-3 hours or we had lows. That was a big stressful. Gradually her sensitivity decreased so that she could go 4 hours between meals without needing snack but we just stopped the snacks and stayed on the same doses. The lantus bumped up over vacation last May when we were struggling and then seemed fine after she settled again so we left it. In early fall we tried a couple of tweaks. We tried dropping ratio at breakfast to 1:50 and had big lows so went to 1:55 and later we tried changing lantus to 2 with big lows and so edged down to 1.75 and seemed good. We are so used to tiny doses. Then in October she got croup and her numbers went sky high particularly after a dose of steroids. After that we have been rocky. Ratios don't seem to work. Something that seems ok one day is completely wrong the next. There are so many variables of course with the activity, type of food, amount of food etc that its hard to just change one thing. Just when it seemed a touch better and we had a whole week that was good then she suddenly jumped again with chaotic numbers followed two weeks later by some awful flu like illness. It seems like we are crushing the last remains of our honeymoon and it just sucks. We have stubborn highs that seem to laugh at my attempts to correct. We are adjusting ratios and being more aggressive but it feels so inadequate. We can't seem to find consistency. She is high much of the time now and more irritable but can't seem to figure out the right ratios vs lantus to keep us steady. We normally only give corrections at meals but in the past few days DH gave a correction a couple hours after morning humalog when she was up nearly to 400. the first couple times it worked well. Yesterday she dropped to 30 after 1:45 min. Yikes! Then after lunch she was back in mid two hundreds and rose to 365 before dinner! I guess I just slightly overdoses her for dinner and then I was up every hour or two all night because she was hanging at 75-85. I didn't want to correct as I was expected it to rise as it has been lately but I kept checking and it only went up to 100 and then drifted back to 85. In the end the numbers were good all night but I had to keep checking because I wasn't sure what was going to happen. Then my other daughter woke me up twice also. So I basically got 5 hours of sleep that was interrupted 3 times and I am at work and absolutely exhausted. I admit that we did not check her every night in the months that we were fairly controlled unless there was something unusual that day in her diet, activity or numbers. In the past couple months I check frequently and have gotten braver about giving corrections at night at least when I felt there was a troublesome dinnner like pasta that was still digesting. But it is sooooo exhausting. I am starting to worry what I might say when a well meaning friend or acquaintance asks me how things are going with DD. Everyone seems to think its just a one time adjustment and you learn what to do and then it is "controlled". Like end of story. Even when things were relatively good it wouldn't have been that crazy to drop to 50 and then up to 300s on any random day especially a party or something atypical. Today when I commented on how tired I was to a friend, she responded with "maybe you should talk to the endocrinologist. It sounds like she is not very well controlled." Yes, I have figured that out actually. And I have spoken to endocrinologist. And I am still losing my mind.