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4MyBoys
Last Activity:
Mar 11, 2014
Joined:
Feb 23, 2008
Messages:
234
Likes Received:
1
Trophy Points:
18

Following 1

Followers 1

Location:
Upstate New York
Occupation:
stay at home mom

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4MyBoys

Approved members, from Upstate New York

4MyBoys was last seen:
Mar 11, 2014
    1. TheFormerLantusFiend
      TheFormerLantusFiend
      Even though most forms of MODY are autosomal dominant, the penetrance of the gene is incomplete. That means that there does not need to be a family history; having one allele is enough to cause MODY, but in 10-50 percent of people with the gene, there's no diabetes. Also, it's possible that it would be mild enough to go undiagnosed. The way you should think of this is that one gene does cause MODY, and most people with that gene do get MODY, but some people with the MODY gene, for whatever reason, don't get it. So you or your husband could have the gene and either not be expressing it, or have such a mild form of diabetes that it hasn't been diagnosed yet.
    2. TheFormerLantusFiend
      TheFormerLantusFiend
      MODY is not what is generally referred to on CWD as "monogenic diabetes" despite being monogenic. If your sons do have MODY, that doesn't mean that they can be treated with pills. However, it may have some meaning in terms of knowing what would happen in their futures in terms of blood sugar and in terms of other health risks, risk for other family members, and so forth.

      I think the odds are high that your sons do not have type 1 because: two are diagnosed without needing insulin, three are diagnosed, you haven't mentioned that any are antibody positive (if they are, then nevermind), and you've mentioned that there's an inappropriate insulin response to food. All of these things, in my mind, point to MODY.
    3. TheFormerLantusFiend
      TheFormerLantusFiend
      Hey, good luck with the adoption process!
      I hope the classes teach something useful.
      Jonah
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  • About

    Location:
    Upstate New York
    Occupation:
    stay at home mom
    Who has diabetes?:
    One child
    Does your family have celiac?:
    No
    Vacation! Scrapbooking! Pets!

    Signature

    Allison, married to my best friend, Andy! Proud mother to 6 amazing kids!
    Gregory, age 14, T1D diagnosed 9/1/06.
    Patrick, age 13. Jasmine, age 11. Brendan, age 11. Marissa, age 9. Sean, age 8.
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