Ellen
11-02-2008, 12:06 PM
I just saw this abstract from 1989 - discussion of implantable sensor - 2 decades ago...
J Biomed Eng. (javascript:AL_get(this, 'jour', 'J Biomed Eng.');) 1989 Sep;11(5):354-61.
Towards implantable glucose sensors: a review.
Wilkins ES (http://forums.childrenwithdiabetes.com/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Wilkins%20ES%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsP anel.Pubmed_DiscoveryPanel.Pubmed_RVAbstractPlus).
Department of Chemical and Nuclear Engineering, University of New Mexico, Albuquerque 87131.
The clinical treatment procedures to monitor and control diabetes mellitus include the use of mechanical devices. Of these devices, closed-loop devices are preferred to open loop devices. However, the development of such devices depends to a great extent on the availability of reliable, long-lasting glucose sensors. In this paper, the status of implantable glucose sensors is reviewed. Glucose sensors are classified and discussed under the following headings: Enzyme catalysed electrodes; metal catalysed sensors; affinity sensors; and coated wire sensors. The relative merits of each of the sensor types are presented and experimental results for both in vitro and in vivo studies are summarized.
J Biomed Eng. (javascript:AL_get(this, 'jour', 'J Biomed Eng.');) 1989 Sep;11(5):354-61.
Towards implantable glucose sensors: a review.
Wilkins ES (http://forums.childrenwithdiabetes.com/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Wilkins%20ES%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsP anel.Pubmed_DiscoveryPanel.Pubmed_RVAbstractPlus).
Department of Chemical and Nuclear Engineering, University of New Mexico, Albuquerque 87131.
The clinical treatment procedures to monitor and control diabetes mellitus include the use of mechanical devices. Of these devices, closed-loop devices are preferred to open loop devices. However, the development of such devices depends to a great extent on the availability of reliable, long-lasting glucose sensors. In this paper, the status of implantable glucose sensors is reviewed. Glucose sensors are classified and discussed under the following headings: Enzyme catalysed electrodes; metal catalysed sensors; affinity sensors; and coated wire sensors. The relative merits of each of the sensor types are presented and experimental results for both in vitro and in vivo studies are summarized.