risk of developing Type 1 if a family member has

[TripleThreat]

I found this table on chances of more diabetics in family if 1 has already. This table is only for type 1 diabetics. With more then one diabetic here i thought some of you would find it interesting as well. found in book "when a child has diabetes" released by jdrf and the hospital for sick children

Risk of developing if family member has it

Sibling(not identical) 1 in 20 chances
identical twin 1 in 2-3 chances
mother 1 in 50-100 chances
father 1 in 16-20 chances

[kel4han]

Wow, that isn't the kind of "luck" I wished for.

My Dad Type 1
Me type 1
Maddison type 1

Hmmm. Maybe we SHOULD play the lottery.

[TracieandJim]

I found this table on chances of more diabetics in family if 1 has already. This table is only for type 1 diabetics. With more then one diabetic here i thought some of you would find it interesting as well. found in book "when a child has diabetes" released by jdrf and the hospital for sick children

Risk of developing if family member has it

Sibling(not identical) 1 in 20 chances
identical twin 1 in 2-3 chances
mother 1 in 50-100 chances
father 1 in 16-20 chances

I wonder? How does this table compute or considered when the sibling already has 2 antibodies?

[piratelight]

I wonder? How does this table compute or considered when the sibling already has 2 antibodies?
I was thinking the same thing since our middle DD is positive for 2.

[bonhamx4]

Our son was dx in 05 at 15 months and our daughter was dx this Jan at age 8, when she went to the hospital the endo team told us that studies have shown that there is a gene in our bloodline that contributes to Type 1. Even though my wife and I do not have D someone in one of our two families did, and it was passed to our children in our genes. Who knows, maybe in the future they can figure out a way to track this and maybe be able to remove it. Maybe as time goes by I or my wife might be dx but not at the moment.

[moco89]

I heard for siblings the risk is about a 3% chance, not a 5% chance. I have a fraternal twin, and that ups his risk of developing type 1 to about 4%. But, supposedly, since I was diagnosed before age six, his risk of developing it goes up to 6%. I read that in a journal one time, and I doubt I could find the publication.

Identical twins do have a 30-50% chance of developing type 1 when the other twin has D.

BTW, the "risk chart" that is being talked about does not take in to account antibodies. This is just risk of developing D in general, when a family member has it.

[cockatiel]

It looks like the table does not take into account multiple instances.

For example, my dh has T1d and my youngest was just diagnosed with it. I am assuming that the chances of my other kids coming down iwth diabetes is HIGHER than if they either just had a father with it or just had a sibling with it.

Oh well -- not much we can do.

I refuse to spend the next years of my life worrying about whether or not my other kids get it. I am VERY thankful (sorry for those of you with diabetic infants/toddlers) that my dd was 12 when diagnosed. I'll take that blessing. Tomorrow has enough problems of its own without me borrowing any!

[RosemaryCinNJ]

Cockatiel....dont be sorry...Im not offended....I understand what you meant by being grateful your daughter wasnt diagnosed as a baby. Just as I am very thankful Amanda was not diagnosed at 12. I know that makes sense only to us parents here...
:) this is all my child will know, but with a 12 year old that is a huge life change for sure....oh it all just stinks dont it???

[KeltonsMom]

Cockatiel....dont be sorry...Im not offended....I understand what you meant by being grateful your daughter wasnt diagnosed as a baby. Just as I am very thankful Amanda was not diagnosed at 12. I know that makes sense only to us parents here...
:) this is all my child will know, but with a 12 year old that is a huge life change for sure....oh it all just stinks dont it???
I have to agree with you about this as well..D sticks period and Kelton remembers what life was like before D came crashing into his life..He is angry about it still, and I do not blame him one bit. He even told me he would have rather been dx'ed as baby so that D would have been all he knew.

[TracieandJim]

I see it this way.. the grass is always greener. Right? Its very hard to watch a child who cant talk and tell you how they feel tho in the same respect a child who talks well, with friends, its like slamming into a brick wall. No offense here either. D is hard, not fun, not fair.. for anyone of any age. I cant imagine even being an adult and dealing with it.

If I am thankful for anything re: D it would be that Samuel was dx'd so young that he will grow up with the 'lifestyle' and be able to accept it as he grows.

T

[Kaylee's Mommy]

Like all charts, the 'chances' will vary slightly.. I was told by Kaylee endo that because Kaylee was dx young (but not as young as some little ones here..) That it increases my older daughter's chance of developing it (beyond the typical 5% of the average sibling). BUT as time goes by, and the distance from diagnosis gets furthar, the chance decreases.. But there could be kids here that fit the senerios to a T and never develope it.. or, like some of the kids, there is NO recent family history, but yet they end up getting T1.

[TracieandJim]

Like all charts, the 'chances' will vary slightly.. I was told by Kaylee endo that because Kaylee was dx young (but not as young as some little ones here..) That it increases my older daughter's chance of developing it (beyond the typical 5% of the average sibling). BUT as time goes by, and the distance from diagnosis gets furthar, the chance decreases.. But there could be kids here that fit the senerios to a T and never develope it.. or, like some of the kids, there is NO recent family history, but yet they end up getting T1.

AGGGHHH. Dont ya just despise the ifs ands and butts! It's ok. Im working on fixing my crystal ball and I will fix all of this! :p

[KatieJane'smom]

Does the chart mention fraternal twins or do you think that just falls into the "sibling" category?

[hawkeyegirl]

Does the chart mention fraternal twins or do you think that just falls into the "sibling" category?

I assume fraternal twins have the same odds as any other siblings. They don't share any more DNA than non-fraternal twin sibs.

[Barry]

I have to agree with you about this as well..D sticks period .

Now there is a Freudian slip. D does stick/////5-7 times a day at my house

[lynn]

http://diabetes.diabetesjournals.org/cgi/reprint/51/1/210.pdf

That article is interesting. It breaks it down into ages and sex and everything.

[KeltonsMom]

Now there is a Freudian slip. D does stick/////5-7 times a day at my house

LOL..I didn't see this until you pointed it out..D sticks here sometimes more than 8x a day :D

[moco89]

I assume fraternal twins have the same odds as any other siblings. They don't share any more DNA than non-fraternal twin sibs.

My mom asked this question to the endo when I was a kid, and the answer was that the risk of the fraternal twin developing D was 1% higher than "normal siblings". I assume this is because the twins are exposed to similar environmental factors simultaneously.

I also read a publication recently about the risk in fraternal twins, but I cannot access the journal, as I am not enrolled at that college this summer.